Breakthroughs

"Our blueprint is simple: provide the best care possible, invent it through research and innovation, then share it with the world."

— Tom Mihaljevic, MD CEO and President and Morton L. Mandel CEO Chair

Cleveland Clinic began with an idea that broke from accepted healthcare practices. We combine clinical care with laboratory research and a robust education program. This model creates medical breakthroughs, decade after decade.

Our Model Made to Innovate

The not-for-profit multispecialty group practice is dedicated to patient care, research and education.

Cleveland Clinic Opens

1921

Cleveland Clinic Locations

Collaboration Locations*

*affiliations, in-country representatives, advisory, and digital health engagements

We are doubling the number of lives we serve, expanding both distance health services and our physical footprint. Cleveland Clinic London opened in winter 2022 to put our care within reach of patients from Europe, Africa and Asia.

Our Global Impact

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Our Mission

Model for Innovation

Strategic Priorities

Global Impact

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Cleveland Clinic creates the future, one breakthrough at a time

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Cleveland Clinic is conducting the first comprehensive brain study to discover the causes of Alzheimer's disease.

Northeast Ohio Region Our main campus and 14 regional hospitals include the top hospital in the U.S. for cardiovascular care and easy access to cancer specialists.

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Irvine Page, MD, led the discovery of serotonin, which unlocked decades of discovery in neuroscience.

Discovery of serotonin

1948

The sickest of the sick come to us when other organizations cannot find answers for them. Among our peers, Cleveland Clinic has the highest load of complex and resource-intense patient cases.

The Cleveland Clinic Difference

PATIENT ACUITY

Patient Volume

PATIENT ACUITY

Patient Volume

Cleveland Clinic cares for the whole person, and we do it with teams of physicians, researchers and caregivers that stretch from London to the Middle East, from Florida to Nevada to Canada.

Cleveland Clinic has big ideas and the plans to fulfill them, with support from partners like you.

Our Strategic Priorities

Cleveland Clinic is in clinical trials of a revolutionary solution for one of the most aggressive forms of breast cancer.

Meet the first patient

The first IBM quantum computer devoted to healthcare will speed research and personalize treatments.

Learn how quantum works

For the first time in the U.S., Cleveland Clinic surgeons removed a life-threatening tumor on the heart of a 26-week-old fetus.

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Cleveland Cinic Canada In 2006, our executive health facility opened in the financial district of downtown Toronto. In 2017, Cleveland Clinic Canada expanded care to sports health services at a second location.

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Cleveland Clinic Abu Dhabi This 364-bed hospital offers more than 50 medical specialties and in 2023 opened a cancer center that offers advanced radiation treatments and precision cellular therapies.

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Cleveland Clinic London Almost 1,500 caregivers offer world class care at an 184-bed hospital and an outpatient facility.

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Cleveland Clinic Florida More than 1,000 beds across 5 hospitals serves thousands of patients from other nations.

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Cleveland Clinic Lou Ruvo Center for Brain Health The Lou Ruvo Center for Brain Health in Las Vegas provides exceptional care for individuals with cognitive disorders, movement disorders and multiple sclerosis.

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Pursuing Answers

Viruses do not care about borders. The global threat requires a global solution. The Sheikha Fatima bint Mubarak Global Center for Pathogen & Human Health Research is already leveraging leading technology to broaden our understanding of and treatments for Mpox, Zika, HIV and COVID-19. Our team will grow to more than 300 scientists in the next seven years.

Preventing Alzheimer's

The Cleveland Clinic Brain Study is our moonshot to reach further than any other organization to unlock the secrets of the body’s ultimate organ. Our study of thousands of people will help us identify therapies for Alzheimer's and other neurological diseases. We are also building a Neurological Institute that will model the hospital of the future. This $1 billion project will use technology and design to begin diagnosing and treating patients as soon as they enter.

Training Caregivers

With a critical shortfall of 2 million skilled positions in healthcare nationally, we are expanding our training of new nurses. We conduct the second largest residency/fellows program in the U.S., and the Cleveland Clinic Lerner College of Medicine has 160 students a year — tuition-free because of donor generosity. These graduates create change around the globe — 15,810 alumni in 77 countries.

Accelerating Discovery

Cleveland Clinic is making a once-in-a-generation investment in our research infrastructure. This $1 billion project will give us new spaces to integrate biomedical expertise and data analytics so we can find ways to prevent disease before it becomes acute. The experts, buildings and computing technology in our Innovation District in Cleveland, Ohio, will partner with other academic research institutions and will accelerate research successes.

Patients Served

Research

Education

Neurology

Global Health

F. Mason Sones, MD, revolutionized the diagnosis and treatment of heart disease by using X-ray images to see a heart’s blood vessels.

Development of coronary angiography

1958

Rene Favaloro, MD, replaced a blocked coronary artery with a vein from the leg to restore blood flow to the heart.

Pioneering coronary artery bypass surgery

1967

William Proudfit, MD, helped create the first computerized medical database, that today informs thousands of research studies every year.

The start of big data

1972

Joseph Hahn, MD, developed electrode grids that enable surgeons to locate where seizures originate in patients with epilepsy.

Discovery of a brain-mapping technique

1980s

LRI has grown into one of the leading research institutes in the nation, with 1,500 scientists and support staff working in 190 laboratories.

Lerner Research Institute opens

1999

LRI has grown into one of the leading research institutes in the nation, with 1,500 scientists and support staff working in 190 laboratories.

First near-total face transplant in U.S.

2008

Such transplants from deceased donors offer hope to women suffering uterine factor infertility.

First North American birth from a uterine transplant

2019

Such transplants from deceased donors offer hope to women suffering uterine factor infertility.

First U.S. program to reach 2,000 heart transplants and 2,000 lung transplants

2020

Paul Marasco, PhD, led the team that engineered a limb that operated with a sense of touch and natural response.

First mind-controlled “bionic arm”

2021

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Hover to learn more about Cleveland Clinic's RECENT breakthroughs

9,900,000+

Cleveland Clinic Worldwide

Annual Research Funding, Thanks to the Catalyst of Philanthropy

$418M

Residents + Fellows in Training

1,900+

Caregivers

70,000+

Caregivers

70,000+

Residents + Fellows in Training

1,900+

Annual Research Funding, Thanks to the Catalyst of Philanthropy

$418M

the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (CCLCM) graduating class reflects on their experience.

9,900,000+

Our 2023 graduates

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Stories

Square Feet

Cost to build

$1B

Inside the world's smartest building

This builDing of hope and inspiration will be filled with light and connections to nature, its every detail intended to be functional, long-lasting and uplifting to the spirit.

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Step inside Cleveland Clinic's Florida Research & Innovation Center, where cutting-edge infectious disease and cancer research is taking place.

Tour Cleveland Clinic's Florida Research & Innovation Center

A message from Cleveland Clinic CEO and President, Tom Mihaljevic, MD

Cleveland Clinic Firsts

Abu Dhabi

London

Northest Ohio region

Florida region

Las Vegas

Canada

Research

Education

NEUROLOGY

Global Health

Transform Lives

Our first century focused on how we could treat acute medical conditions. And we changed human health. In our second century we are breaking through to prevent those diseases. And we’ll change the world. With your passion, partnership and bold philanthropy.

Strategic Priorities

Global Impact

Model for Innovation

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Visit our website to learn about the Executive Health Program at Cleveland Clinic.

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Students at Cleveland Clinic Children’s Center for Autism enjoy instruction tailored to their academic, communication and socialization needs. Children with autism may exhibit repetitive behaviors; this student’s scripting symptoms include gestures.